Ibuprofen vs acetaminophen vs naproxen LP

Ibuprofen vs acetaminophen vs naproxen LP

What’s the difference between acetaminophen, ibuprofen, and naproxen?

All three nonprescription products are approved for the relief of pain, by the U.S. Food and Drug Administration. The main difference between the three products lie within the pharmacokinetics. All three products have a different time to reach maximal concentration(Cmax) in the human body and all have varying half-lives, or the duration of action.

Product Cmax Half Life
Acetaminophen 0.5 -1 hour 3 hours
Ibuprofen 1 -2 hour(s) 1.8 – 2.4 hours
Naproxen 1 hour 8 - 12 hours